Sickened

You take a -2 penalty to attack rolls, weapon damage rolls, saving throws, skill checks, and ability checks.

Source

Core Rulebook pg. 277


Dragonscript

Effect

bonus -2 to [character.attack.melee, character.attack.ranged, character.attack.thrown, character.damage.melee, character.damage.ranged, character.damage.thrown, character.fortitude, character.will, character.reflex, character.initiative,character.acrobatics, character.athletics, character.bluff, character.computers, character.culture, character.diplomacy, character.disguise, character.engineering, character.intimidate, character.lifeScience, character.medicine, character.mysticism, character.perception, character.physicalScience, character.piloting, character.profession, character.senseMotive, character.sleightOfHand, character.stealth, character.survival, character.strength.modifier, character.dexterity.modifier, character.constitution.modifier, character.intelligence.modifier, character.wisdom.modifier, character.charisma.modifier] as misc;
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